Molecular Formula: (C6.2H10.3O1.35N0.65Na0.35)~72
CAS Number: [326856-53-5]
Formula Weight: ~ 9 kDa
Solubility: up to 20% in water
Appearance: White Solid
Amphipols are a new class of surfactants that serve as stabilizers of membrane proteins in aqueous solutions. Amphipols can substitute out the detergents used to extract membrane proteins, keeping them soluble in detergent-free aqueous solution while stabilizing them biochemically.
Applications:
• Stabilization of native membrane protein structure
•
In vitro functional studies
• Facilitating membrane protein folding / refolding
• NMR
• Electron microscopy
• Immobilization of membrane proteins onto solid surface
Citation(s):
1. Zoonens & Popot, J. Membr. Biol. 247:759-796, 2014.
2. For additional Amphipol references: http://www.ibpc.fr/amphipol
No data available.